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Culture Club Msg Board > How do cryptic peptides differ from neoantigens?
How do cryptic peptides differ from neoantigens?
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Apr 20, 2026
8:32 PM 		Neoantigens are highly immunogenic but often patient-specific and costly to identify, limiting their scalability. In contrast, TAA-derived cryptic peptides have low self-tolerance and broader applicability across patients, offering a more universal vaccine strategy while maintaining immunogenic potential after optimization.


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