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Culture Club Msg Board > Fragile X Syndrome
Fragile X Syndrome
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May 18, 2026
1:24 AM 		Fragile X Syndrome (FXS) is the most common inherited form of intellectual disability and a leading monogenic cause of autism spectrum disorder (ASD). It arises from a CGG trinucleotide repeat expansion in the FMR1 gene, leading to its transcriptional silencing and loss of the Fragile X Mental Retardation Protein (FMRP).


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